5-Chloro-2-thiophenesulfonyl chloride
5-Chlorothiophene-2-sulfonyl chloride
CAS: 2766-74-7
Molecular Formula: C4H2Cl2O2S2
5-Chloro-2-thiophenesulfonyl chloride - Names and Identifiers
| Name | 5-Chlorothiophene-2-sulfonyl chloride |
| Synonyms | TIMTEC-BB SBB003378 ART-CHEM-BB B019398 5-CHLORO-2-THIENYLSULFONYL CHLORIDE 5-CHLOROTHIOPHENESULPHONYL CHLORIDE 5-Chlorothiophene-2-sulfonyl chloride 5-Chloro-2-thiophenesulfonyl chloride 5-CHLOROTHIOPHENE-2-SULFONYL CHLORIDE 5-CHLORO-2-THIOPHENESULFONYL CHLORIDE 5-CHLOROTHIOPHENE-2-SULPHONYL CHLORIDE |
| CAS | 2766-74-7 |
| InChI | InChI=1/C4H2Cl2O2S2/c5-3-1-2-4(9-3)10(6,7)8/h1-2H |
| InChIKey | SORSTNOXGOXWAO-UHFFFAOYSA-N |
5-Chloro-2-thiophenesulfonyl chloride - Physico-chemical Properties
| Molecular Formula | C4H2Cl2O2S2 |
| Molar Mass | 217.09 |
| Density | 1.623 g/mL at 25 °C (lit.) |
| Melting Point | 25-28°C |
| Boling Point | 112-117 °C (lit.) |
| Flash Point | >230°F |
| Water Solubility | Not miscible in water. |
| Appearance | solid |
| Specific Gravity | 1.623 |
| Color | Colorless to Yellow to Orange |
| BRN | 130710 |
| Storage Condition | 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | n20/D 1.586(lit.) |
5-Chloro-2-thiophenesulfonyl chloride - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R34 - Causes burns R29 - Contact with water liberates toxic gas R14 - Reacts violently with water |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S28A - S25 - Avoid contact with eyes. |
| UN IDs | UN 3265 8/PG 2 |
| WGK Germany | 3 |
| HS Code | 29349990 |
| Hazard Note | Corrosive |
| Hazard Class | 8 |
| Packing Group | II |
5-Chloro-2-thiophenesulfonyl chloride - Introduction
chloride is an organic compound with the chemical formula C4H2ClNO2S. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: chloride is a colorless to yellowish liquid.
-Melting point and boiling point: Its melting point is -7 to -5 ℃, and its boiling point is 110 to 112 ℃.
-Solubility: chloride is soluble in organic solvents such as ether and methylene chloride.
Use:
-Chemical intermediates: chloride can be used as an important intermediate in organic synthesis, used in the synthesis of organic compounds such as drugs, dyes and pesticides.
-Drug manufacturing: This compound is widely used in the pharmaceutical industry for the synthesis of antiepileptic drugs and other drugs.
Method:
-the preparation method of chloride is usually obtained by reacting 5-chloro-2-thiophenecarboxamide with sulfonyl chloride. Under the reaction conditions, the reaction can be carried out under alkaline conditions to form chloride.
Safety Information: chloride is an irritating compound and should be avoided from contact with skin and eyes. Appropriate personal protective measures such as gloves, goggles and chemical protective clothing must be taken to handle the compound.
-When storing and handling the compound, care should be taken to avoid contact with oxidants and flammable materials to prevent fire or explosion accidents.
-When using this compound, it should be operated in a well-ventilated place to avoid inhaling its vapor.
Nature:
-Appearance: chloride is a colorless to yellowish liquid.
-Melting point and boiling point: Its melting point is -7 to -5 ℃, and its boiling point is 110 to 112 ℃.
-Solubility: chloride is soluble in organic solvents such as ether and methylene chloride.
Use:
-Chemical intermediates: chloride can be used as an important intermediate in organic synthesis, used in the synthesis of organic compounds such as drugs, dyes and pesticides.
-Drug manufacturing: This compound is widely used in the pharmaceutical industry for the synthesis of antiepileptic drugs and other drugs.
Method:
-the preparation method of chloride is usually obtained by reacting 5-chloro-2-thiophenecarboxamide with sulfonyl chloride. Under the reaction conditions, the reaction can be carried out under alkaline conditions to form chloride.
Safety Information: chloride is an irritating compound and should be avoided from contact with skin and eyes. Appropriate personal protective measures such as gloves, goggles and chemical protective clothing must be taken to handle the compound.
-When storing and handling the compound, care should be taken to avoid contact with oxidants and flammable materials to prevent fire or explosion accidents.
-When using this compound, it should be operated in a well-ventilated place to avoid inhaling its vapor.
Last Update：2024-04-09 02:00:44
